The CTI CRC Phase I unit is a state-of-the-art facility designed specifically to conduct early phase clinical pharmacology trials. Additionally, the Phase I unit is just minutes from downtown Cincinnati, Ohio, and its surrounding suburbs, thus providing convenient access to a large metropolitan population. 

CTI is well versed with the intricacies and challenges associated with Phase I studies and has successfully completed phase I trials involving healthy volunteers and various patient populations.  Our years of experience in the conduct of clinical trials and the execution of early phase studies have positioned CTI as one of the premier clinical research sites in the United States. 

We attend industry meetings and are members of many pharmacology societies, including the American College of Clinical Pharmacology (ACCP) and the American Society for Clinical Pharmacology and Therapeutics (ASCPT).

Phase I Unit Experience

  • First-in-human
  • SAD / MAD
  • PK / PD
  • Monoclonal antibodies / Biologics
  • Proof-of-concept
  • Bioavailability / Bioequivalence
  • Crossover designs
  • Food effect
  • Drug-interaction
  • CYP2D6 metabolizers
  • Vaccine
  • Adaptive design

Phase I Unit Capabilities

  • 30 bed capacity
  • On-site clinical laboratory
  • On-site investigational pharmacy
  • Holter-Monitoring
  • Neuro-cognitive testing
  • EEG / Polysommnography
  • Full body plethysmograph
  • -70ºC and -20ºC freezers with emergency back-up
  • Multiple recreation areas for subjects
  • On-site compounding pharmacy

CTI Clinical Research Center