Therapeutic Areas Nephrology


Nephrology is a diverse area of research encompassing several diseases that affect renal function, either as a primary diagnosis or as a secondary complication from an underlying problem. CTI has consistently worked in this area for 20 years. Past and ongoing trials have ranged from small first-in-human trials to large multi-national registries. Our Medical Directors, including a former transplant surgeon, work closely with the rest of our organization so that project teams are familiar with renal diseases and associated complications. We specialize in the unique challenges associated with nephrology populations, from mild to moderate renal impairment to dialysis, with an emphasis on chronic kidney disease. We attend industry meetings and are members of many nephrology societies, including the American Society for Nephrology (ASN), American Society of Pediatric Nephrology (ASPN), and the International Society of Nephrology (ISN).

Some of our adult and pediatric experience includes:

  • Acute kidney injury (AKI)
  • Alport syndrome
  • Atypical hemolytic uremic syndrome (aHUS)
  • Chronic kidney disease (CKD)
  • Chronic allograft injury
  • Chronic hepatitis C virus (HCV)
  • Contrast-induced nephropathy (CIN)
  • Cystinosis
  • Delayed graft function (DGF)
  • Diabetes-related renal disease
  • Dialysis/Hemodialysis vascular access
  • End stage renal disease
  • Ischemia reperfusion injury (IRI)
  • Kidney transplant
  • Organ rejection (acute cellular rejection [ACR] and antibody mediated rejection [AMR])
  • Renal fibrosis
  • Renal function

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